11/28/2023 0 Comments Incontrol intensity![]() ![]() However, the programme is facing new challenges due to the rebound of transmission in some areas, probably influenced by changes in environmental and social factors, particularly in lake regions, which exhibit more ecological complexity than other regions. China has dropped significantly as a result of sustained efforts and updated intervention strategies within the context of the national schistosomiasis control programme. Over the last few decades, the prevalence and burden of disease in P.R. China, with an estimated 11.6 million people infected as indicated by epidemiological data from the 1950s. ![]() ![]() Schistosomiasis was endemic in 12 provinces of P.R. The disease is a serious threat to human health and contributes to poverty in endemic regions, and has been prevalent in P.R. China), the Republic of the Philippines and Indonesia. Human schistosomiasis japonica is caused by infection with Schistosoma japonicum, a parasitic flatworm (Platyhelminth: Trematoda), and a significant cause of morbidity in oriental Asia, including the People’s Republic of China (P.R. In the absence of simultaneous R 0 estimations for villages not under control interventions (such villages do not currently exist in China), it is difficult to assess whether control strategies have had a substantial impact on levels of transmission, as the parasite population would still be able to maintain itself at an endemic level, highlighting the difficulties faced by elimination efforts. Ignoring seasonality tends to underestimate R 0 values albeit only marginally. Our modified version of the Barbour model to account for seasonal fluctuations in transmission has the potential to provide better estimations of infection risk than previous models. Results show that the value of the basic reproduction ratio, R 0, of Liaonan village, Xingzi county is located between 1.064 and 1.066 (very close to 1), for schistosomiasis transmission during 2006 to 2010, after intensification of control efforts. The explicit formula of the basic reproduction ratio for the SV-modified Barbour’s model is derived. We perform numerical simulations and parametric sensitivity analysis to understand local transmission conditions and compare values of the basic reproductive ratio with and without seasonal fluctuations. japonicum in humans we parameterise such expressions with surveillance data to investigate the conditions for persistence or elimination of the disease in the study village. We use mathematical tools for stability analysis of periodic systems and derive expressions for the basic reproduction ratio of S. japonicum using a modified version of Barbour’s model to account for seasonal variation (SV), and investigate the effectiveness of the control strategy adopted in Liaonan village of Xingzi county, Jiangxi Province. In this paper, we characterize the transmission dynamics of S. Seasonal fluctuations in transmission may have the potential to impact on the population dynamics of schistosomiasis, yet no model of S. Mathematical modelling of schistosomiasis transmission has been undertaken in order to assess and project the effects of various control strategies for elimination of the disease. Schistosomiasis japonica, caused by infection with Schistosoma japonicum, is still recognized as a major public health problem in the Peoples’ Republic of China.
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